Josh Jacobs rushed for 106 yards and three touchdowns and the defense forced three turnovers to lift the host Green Bay Packers to a 38-10 rout of the slumping San Francisco 49ers on Sunday.Green Bay (8-3) avenged last season’s playoff defeat to the reigning NFC champion 49ers, who lost their second game in a row to fall to 5-6.Jordan Love passed for 163 yards and two touchdowns, helping the Packers to a season high in points.Green Bay scored the first 17 points, moving the ball efficiently against a San Francisco defense whose inactives included defensive end Joey Bosa (hip, oblique) and cornerback Charvarius Ward (personal matter).Injuries on offense also took a toll. Brandon Allen started at quarterback for San Francisco in place of Brock Purdy, who was out with a sore right (throwing) shoulder, while left tackle Trent Williams also missed the game.Love hit Tucker Kraft for an 11-yard touchdown pass on the opening drive. The Packers made it 10-0 on Brandon McManus’ 51-yard field goal late in the first quarter and surged ahead 17-0 on Jacobs’ 1-yard TD run with 6:33 left in the second.Jacobs struck again with 4:28 remaining in the third quarter on another score from a yard out. Green Bay capitalized on a short field after Xavier McKinney intercepted Allen and returned the ball to the San Francisco 26.Following a Jake Moody field goal for the 49ers, the Packers scored another touchdown off a takeaway. Jacobs sealed the third three-TD effort of his career with 10:59 left in the game, shortly after Allen fumbled on Lukas Van Ness’ sack and Kenny Clark recovered at the Niners’ 16.